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Cross talk of chromosome instability, CpG island methylator phenotype and mismatch repair in colorectal cancer

Colorectal cancer is a severe cancer associated with a high prevalence and fatality rate. There are three major mechanisms for colorectal cancer: (1) Chromosome instability (CIN), (2) CpG island methylator phenotype (CIMP) and (3) mismatch repair (MMR), of which CIN is the most common type. However,...

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Detalles Bibliográficos
Autores principales: Zhang, Tian-Ming, Huang, Tao, Wang, Rong-Fei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6036478/
https://www.ncbi.nlm.nih.gov/pubmed/30008861
http://dx.doi.org/10.3892/ol.2018.8860