Suppressed epithelial-mesenchymal transition and cancer stem cell properties mediate the anti-cancer effects of ethyl pyruvate via regulation of the AKT/nuclear factor-κB pathway in prostate cancer cells

Castration-resistant prostate cancer (CRPC) is a leading cause of mortality among cases of prostate cancer (PCa). Current treatment options for CRPC are limited. Ethyl pyruvate (EP), a lipophilic derivative of pyruvic acid, has been reported to have antitumor activities. In the present study, the ef...

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Detalles Bibliográficos
Autores principales: Huang, Bin, Lv, Dao-Jun, Wang, Chong, Shu, Fang-Peng, Gong, Zhi-Cheng, Xie, Tao, Yu, Yu-Zhong, Song, Xian-Lu, Xie, Jia-Jia, Li, Sen, Liu, Ya-Meng, Qi, Huan, Zhao, Shan-Chao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2018
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6036506/
https://www.ncbi.nlm.nih.gov/pubmed/30008929
http://dx.doi.org/10.3892/ol.2018.8958

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6036506/
https://www.ncbi.nlm.nih.gov/pubmed/30008929
http://dx.doi.org/10.3892/ol.2018.8958

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