Leptospira interrogans thermolysin refolded at high pressure and alkaline pH displays proteolytic activity against complement C3

Enzymes from the thermolysin family are crucial factors in the pathogenesis of several diseases caused by bacteria and are potential targets for therapeutic interventions. Thermolysin encoded by the gene LIC13322 of the causative agent of leptospirosis, Leptospira interrogans, was shown to cleave pr...

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Detalles Bibliográficos
Autores principales: Chura-Chambi, Rosa Maria, Fraga, Tatiana Rodrigues, da Silva, Ludmila Bezerra, Yamamoto, Bruno Bernardi, Isaac, Lourdes, Barbosa, Angela Silva, Morganti, Ligia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6036645/
https://www.ncbi.nlm.nih.gov/pubmed/29992100
http://dx.doi.org/10.1016/j.btre.2018.e00266

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6036645/
https://www.ncbi.nlm.nih.gov/pubmed/29992100
http://dx.doi.org/10.1016/j.btre.2018.e00266

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