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Leptospira interrogans thermolysin refolded at high pressure and alkaline pH displays proteolytic activity against complement C3
Enzymes from the thermolysin family are crucial factors in the pathogenesis of several diseases caused by bacteria and are potential targets for therapeutic interventions. Thermolysin encoded by the gene LIC13322 of the causative agent of leptospirosis, Leptospira interrogans, was shown to cleave pr...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Elsevier
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6036645/ https://www.ncbi.nlm.nih.gov/pubmed/29992100 http://dx.doi.org/10.1016/j.btre.2018.e00266 |