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Functional redundancy in Echinocandin B in-cluster transcription factor ecdB of Emericella rugulosa NRRL 11440

Echinocandin B is a potent antifungal against the majority of fungal pathogens and its biosynthesis occurred by ecd and hty gene clusters in Emericella rugulosa NRRL 11440. We elucidated the functional necessity of in-clustered transcription factor; ecdB in the production of echinocandin B. We delet...

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Detalles Bibliográficos
Autores principales: Kumar, Arvind, Jaiswal, Varun, Kumar, Vinay, Dey, Amitava, Kumar, Antresh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6036647/
https://www.ncbi.nlm.nih.gov/pubmed/29992098
http://dx.doi.org/10.1016/j.btre.2018.e00264