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PDE4a predicts poor prognosis and promotes metastasis by inducing epithelial-mesenchymal transition in hepatocellular carcinoma

Phosphodiesterases (PDEs) was found to be involved in a variety of cancer pathologies by modulating the degradation of levels of cAMP/cGMP. However, the prognostic significance and biological effect of PDE4a in hepatocellular carcinoma (HCC) have not been understood completely. In the present study,...

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Detalles Bibliográficos
Autores principales: Peng, Yanghong, Li, Yijun, Tian, Yu, Ao, Guokun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6036708/
https://www.ncbi.nlm.nih.gov/pubmed/30026835
http://dx.doi.org/10.7150/jca.24079