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WDR1 Promotes Cell Growth and Migration and Contributes to Malignant Phenotypes of Non-small Cell Lung Cancer through ADF/cofilin-mediated Actin Dynamics

The characteristic of carcinoma is cell migration and invasion, which involve in strong actin dynamics. Regulations of actin dynamics have been implicated in cancer cell migration and tumor progression. WDR1 (WD-repeat domain 1) is a major cofactor of the actin depolymerizing factor (ADF)/cofilin, s...

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Detalles Bibliográficos
Autores principales: Yuan, Baiyin, Zhang, Ruirui, Hu, Jisheng, Liu, Zhongying, Yang, Chao, Zhang, Tongcun, Zhang, Chenxi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6036740/
https://www.ncbi.nlm.nih.gov/pubmed/29989053
http://dx.doi.org/10.7150/ijbs.23845