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HUWE1 controls the development of non-small cell lung cancer through down-regulation of p53

Lung cancer is the most frequent cancer type and the leading cause of tumor-associated deaths worldwide. TP53 is an important tumor suppressor gene and is frequently inactivated in lung cancer. E3 ligases targeting p53, such as MDM2, are involved in the development of lung cancer. The E3 ligase HUWE...

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Detalles Bibliográficos
Autores principales: Yang, Dong, Cheng, Daomei, Tu, Qiu, Yang, Huihui, Sun, Bin, Yan, Lanzhen, Dai, Hongjuan, Luo, Jierong, Mao, Bingyu, Cao, Yi, Yu, Xiaoping, Jiang, Hua, Zhao, Xudong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6037029/
https://www.ncbi.nlm.nih.gov/pubmed/30026863
http://dx.doi.org/10.7150/thno.24401