Cargando…
HUWE1 controls the development of non-small cell lung cancer through down-regulation of p53
Lung cancer is the most frequent cancer type and the leading cause of tumor-associated deaths worldwide. TP53 is an important tumor suppressor gene and is frequently inactivated in lung cancer. E3 ligases targeting p53, such as MDM2, are involved in the development of lung cancer. The E3 ligase HUWE...
Autores principales: | Yang, Dong, Cheng, Daomei, Tu, Qiu, Yang, Huihui, Sun, Bin, Yan, Lanzhen, Dai, Hongjuan, Luo, Jierong, Mao, Bingyu, Cao, Yi, Yu, Xiaoping, Jiang, Hua, Zhao, Xudong |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Ivyspring International Publisher
2018
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6037029/ https://www.ncbi.nlm.nih.gov/pubmed/30026863 http://dx.doi.org/10.7150/thno.24401 |
Ejemplares similares
-
Ubiquitination by HUWE1 in tumorigenesis and beyond
por: Kao, Shih-Han, et al.
Publicado: (2018) -
Increased p53 signaling impairs neural differentiation in HUWE1-promoted intellectual disabilities
por: Aprigliano, Rossana, et al.
Publicado: (2021) -
The ubiquitin-like modifier FAT10 covalently modifies HUWE1 and strengthens the interaction of AMBRA1 and HUWE1
por: Mueller, Stefanie, et al.
Publicado: (2023) -
p53 Ubiquitination Comediated by HUWE1 and TRAF6 Contributes to White Spot Syndrome Virus Infection in Crustacean
por: Gong, Yi, et al.
Publicado: (2022) -
A conformational switch regulates the ubiquitin ligase HUWE1
por: Sander, Bodo, et al.
Publicado: (2017)