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Distinct immune signatures in directly treated and distant tumors result from TLR adjuvants and focal ablation

Both adjuvants and focal ablation can alter the local innate immune system and trigger a highly effective systemic response. Our goal is to determine the impact of these treatments on directly treated and distant disease and the mechanisms for the enhanced response obtained by combinatorial treatmen...

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Detalles Bibliográficos
Autores principales: Chavez, Michael, Silvestrini, Matthew T., Ingham, Elizabeth S., Fite, Brett Z., Mahakian, Lisa M., Tam, Sarah M., Ilovitsh, Asaf, Monjazeb, Arta M., Murphy, William J., Hubbard, Neil E., Davis, Ryan R., Tepper, Clifford G., Borowsky, Alexander D., Ferrara, Katherine W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6037035/
https://www.ncbi.nlm.nih.gov/pubmed/30026870
http://dx.doi.org/10.7150/thno.25613