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Drug-delivering-drug platform-mediated potent protein therapeutics via a non-endo-lysosomal route

Protein therapeutics is playing an increasingly critical role in treatment of human diseases. However, current vectors are captured by the digestive endo-lysosomal system, which results in an extremely low fraction (<2%) of protein being released in the cytoplasm. This paper reports a drug-delive...

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Detalles Bibliográficos
Autores principales: Xin, Xiaofei, Teng, Chao, Du, Xiaoqing, Lv, Yaiqi, Xiao, Qingqing, Wu, Yubing, He, Wei, Yin, Lifang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6037042/
https://www.ncbi.nlm.nih.gov/pubmed/30026860
http://dx.doi.org/10.7150/thno.23804