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By blocking hexokinase-2 phosphorylation, limonin suppresses tumor glycolysis and induces cell apoptosis in hepatocellular carcinoma
INTRODUCTION: The purpose of present study was to investigate the effect of limonin on tumor glycolysis and the underlying mechanisms in hepatocellular carcinoma (HCC). METHODS: Cell proliferation and colony formation assays were performed to evaluate the potency of limonin against HCC cells in vitr...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove Medical Press
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6037266/ https://www.ncbi.nlm.nih.gov/pubmed/30013360 http://dx.doi.org/10.2147/OTT.S165220 |