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Ginkgo biloba extract and its diterpene ginkgolide constituents ameliorate the metabolic disturbances caused by recombinant tissue plasminogen activator in rat prefrontal cortex

INTRODUCTION: Although recombinant tissue plasminogen activator (rtPA) is a widely used therapy in patients with acute ischemic stroke, rtPA-induced toxicity or its adverse effects have been reported in our previous studies. However, Ginkgo biloba extract (GBE) may provide neuroprotective effects ag...

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Detalles Bibliográficos
Autores principales: Chen, Zhi, Bai, Shunjie, Hu, Qingchuan, Shen, Peng, Wang, Ting, Liang, Zihong, Wang, Wei, Qi, Xunzhong, Xie, Peng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6037272/
https://www.ncbi.nlm.nih.gov/pubmed/30013348
http://dx.doi.org/10.2147/NDT.S167448