Rosuvastatin calcium nanoparticles: Improving bioavailability by formulation and stabilization codesign

PURPOSE: Rosuvastatin calcium (ROSCa) is a poorly soluble drug with bioavailability not exceeding 20%. Decreasing the particle size may enhance its solubility, dissolution rate and bioavailability. Therefore, the aim of the current study is to prepare ROSCa nanoparticles by wet milling technique usi...

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Detalles Bibliográficos
Autores principales: Alshora, Doaa H., Ibrahim, Mohamed A., Elzayat, Ehab, Almeanazel, Osaid T., Alanazi, Fars
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6037357/
https://www.ncbi.nlm.nih.gov/pubmed/29985967
http://dx.doi.org/10.1371/journal.pone.0200218

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6037357/
https://www.ncbi.nlm.nih.gov/pubmed/29985967
http://dx.doi.org/10.1371/journal.pone.0200218

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