Cargando…

Rosuvastatin calcium nanoparticles: Improving bioavailability by formulation and stabilization codesign

PURPOSE: Rosuvastatin calcium (ROSCa) is a poorly soluble drug with bioavailability not exceeding 20%. Decreasing the particle size may enhance its solubility, dissolution rate and bioavailability. Therefore, the aim of the current study is to prepare ROSCa nanoparticles by wet milling technique usi...

Descripción completa

Detalles Bibliográficos
Autores principales:	Alshora, Doaa H., Ibrahim, Mohamed A., Elzayat, Ehab, Almeanazel, Osaid T., Alanazi, Fars
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2018
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6037357/ https://www.ncbi.nlm.nih.gov/pubmed/29985967 http://dx.doi.org/10.1371/journal.pone.0200218

Ejemplares similares

Defining the process parameters affecting the fabrication of rosuvastatin calcium nanoparticles by planetary ball mill
por: Alshora, Doaa, et al.
Publicado: (2019)

Nanotechnology as a tool to overcome the bariatric surgery malabsorption
por: Almeanazel, Osaid, et al.
Publicado: (2020)

Formulation of sublingual promethazine hydrochloride tablets for rapid relief of motion sickness
por: Alyami, Hamad S, et al.
Publicado: (2021)

Dissolution and bioavailability improvement of bioactive apigenin using solid dispersions prepared by different techniques
por: Alshehri, Sultan M., et al.
Publicado: (2019)

Enhancing Oral Bioavailability of Apigenin Using a Bioactive Self-Nanoemulsifying Drug Delivery System (Bio-SNEDDS): In Vitro, In Vivo and Stability Evaluations
por: Kazi, Mohsin, et al.
Publicado: (2020)

Crosstalk of low density lipoprotein and liposome as a paradigm for targeting of 5-fluorouracil into hepatic cells: cytotoxicity and liver deposition
por: Alanazi, Saleh A., et al.
Publicado: (2021)

Optimization of Bromocriptine-Mesylate-Loaded Polycaprolactone Nanoparticles Coated with Chitosan for Nose-to-Brain Delivery: In Vitro and In Vivo Studies
por: Badran, Mohamed M., et al.
Publicado: (2023)

Formulation and pharmacokinetics of multi-layered matrix tablets: Biphasic delivery of diclofenac
por: Elzayat, Ehab Mostafa, et al.
Publicado: (2017)

Enhanced Codelivery of Gefitinib and Azacitidine for Treatment of Metastatic-Resistant Lung Cancer Using Biodegradable Lipid Nanoparticles
por: Elzayat, Ehab M., et al.
Publicado: (2023)

Tripling the Bioavailability of Rosuvastatin Calcium Through Development and Optimization of an In-Situ Forming Nanovesicular System
por: Elsayed, Ibrahim, et al.
Publicado: (2019)

Evaluation of wound healing activity of henna, pomegranate and myrrh herbal ointment blend
por: Elzayat, Ehab M., et al.
Publicado: (2018)

Formulation of Glibenclamide proniosomes for oral administration: Pharmaceutical and pharmacodynamics evaluation
por: Alshora, Doaa, et al.
Publicado: (2023)

Fabrication and characterization of orodispersible films loaded with solid dispersion to enhance Rosuvastatin calcium bioavailability
por: Zaki, Randa Mohammed, et al.
Publicado: (2023)

Enhanced Dissolution of Luteolin by Solid Dispersion Prepared by Different Methods: Physicochemical Characterization and Antioxidant Activity
por: Alshehri, Sultan, et al.
Publicado: (2020)

The Use of Calcium Phosphate-Based Starter Pellets for the Preparation of Sprinkle IR MUPS Formulation of Rosuvastatin Calcium
por: Cal, Krzysztof, et al.
Publicado: (2023)

Formulation and Evaluation of Transdermal Gel Containing Tacrolimus-Loaded Spanlastics: In Vitro, Ex Vivo and In Vivo Studies
por: Zaki, Randa Mohammed, et al.
Publicado: (2022)

Phase 1 Pharmacokinetic Study of AZD5718 in Healthy Volunteers: Effects of Coadministration With Rosuvastatin, Formulation and Food on Oral Bioavailability
por: Ericsson, Hans, et al.
Publicado: (2019)

Formulation and Optimization of Nanospanlastics for Improving the Bioavailability of Green Tea Epigallocatechin Gallate
por: Mazyed, Eman A., et al.
Publicado: (2021)

Development and Characterization of Eudragit-RL-100-Based Aceclofenac Sustained-Release Matrix Pellets Prepared via Extrusion/Spheronization
por: Ibrahim, Mohamed Abbas, et al.
Publicado: (2021)

Validated High-Performance Liquid Chromatographic Method for the Estimation of Rosuvastatin Calcium in Bulk and Pharmaceutical Formulations
por: Ashour, Safwan, et al.
Publicado: (2011)

Novel nanomicelle formulation to enhance bioavailability and stability of curcuminoids
por: Hatamipour, Mahdi, et al.
Publicado: (2019)

Preparation and optimization of microemulsion of rosuvastatin calcium
por: Patel, Zalak B., et al.
Publicado: (2012)

Developed simvastatin chitosan nanoparticles co-crosslinked with tripolyphosphate and chondroitin sulfate for ASGPR-mediated targeted HCC delivery with enhanced oral bioavailability
por: Faris, Tarek M., et al.
Publicado: (2020)

Polymeric nanocomposite hydrogel scaffold for jawbone regeneration: The role of rosuvastatin calcium-loaded silica nanoparticles
por: Adel, Islam M., et al.
Publicado: (2023)

Influence of the microwave technology on solid dispersions of mefenamic acid and flufenamic acid
por: Alshehri, Sultan, et al.
Publicado: (2017)

Higher Bioavailability of Calcium in Chickens With a Novel In-Feed Pharmaceutical Formulation
por: Carrillo, Lizbeth, et al.
Publicado: (2020)

The role of sodium lauryl sulfate on formulation of directly compressed tablets containing simvastatin and aspirin: Effect on drugs dissolution and gastric mucosa
por: Alshora, Doaa H., et al.
Publicado: (2022)

Evaluation of the bioavailability of hydrocortisone when prepared as solid dispersion
por: Altamimi, Mohammad A., et al.
Publicado: (2019)

Exploring the molecular reorientations in amorphous rosuvastatin calcium
por: Belozerova, N. M., et al.
Publicado: (2020)

Handbook of hardware/software codesign
por: Ha, Soonhoi, et al.
Publicado: (2017)

Eudragit nanoparticles containing genistein: formulation, development, and bioavailability assessment
por: Tang, Jingling, et al.
Publicado: (2011)

Formulation and In Vivo Evaluation of Biofilm Loaded with Silver Sulfadiazine for Burn Healing
por: Alshora, Doaa, et al.
Publicado: (2023)

Analytical Study for the Charge-Transfer Complexes of Rosuvastatin Calcium with π-Acceptors
por: Alzoman, Nourah Z., et al.
Publicado: (2013)

Nanoemulsions as delivery systems for lipophilic nutraceuticals: strategies for improving their formulation, stability, functionality and bioavailability
por: Choi, Seung Jun, et al.
Publicado: (2020)

Formulation Strategies for Improving the Stability and Bioavailability of Vitamin D-Fortified Beverages: A Review
por: Vieira, Elsa F., et al.
Publicado: (2022)

Role of Alternative Lipid Excipients in the Design of Self-Nanoemulsifying Formulations for Fenofibrate: Characterization, in vitro Dispersion, Digestion and ex vivo Gut Permeation Studies
por: Alshamsan, Aws, et al.
Publicado: (2018)

Rapid Analysis of Glibenclamide Using an Environmentally Benign Stability-Indicating RP-HPLC Method
por: Haq, Nazrul, et al.
Publicado: (2014)

Dissolution Enhancement of Rosuvastatin Calcium by Liquisolid Compact Technique
por: Kapure, V. J., et al.
Publicado: (2013)

Design, development, and characterization of amorphous rosuvastatin calcium tablets
por: González, Rocío, et al.
Publicado: (2022)

Self-nanoemulsifying ramipril tablets: a novel delivery system for the enhancement of drug dissolution and stability
por: Alhasani, Khalid F, et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_6b9vgqe3h7ou4ab1sl7a1n3bqj