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African and Asian strains of Zika virus differ in their ability to infect and lyse primitive human placental trophoblast

Zika virus (ZIKV) drew worldwide attention when a recent epidemic was linked to fetal microcephaly. Here we used human embryonic stem cell derived trophoblasts as a model for primitive placental trophoblast to test the hypothesis that there are differences in how the two genetically distinct ZIKV li...

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Detalles Bibliográficos
Autores principales: Sheridan, Megan A., Balaraman, Velmurugan, Schust, Danny J., Ezashi, Toshihiko, Roberts, R. Michael, Franz, Alexander W. E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6037361/
https://www.ncbi.nlm.nih.gov/pubmed/29985932
http://dx.doi.org/10.1371/journal.pone.0200086