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A stable mode of bookmarking by TBP recruits RNA polymerase II to mitotic chromosomes

Maintenance of transcription programs is challenged during mitosis when chromatin becomes condensed and transcription is silenced. How do the daughter cells re-establish the original transcription program? Here, we report that the TATA-binding protein (TBP), a key component of the core transcription...

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Detalles Bibliográficos
Autores principales: Teves, Sheila S, An, Luye, Bhargava-Shah, Aarohi, Xie, Liangqi, Darzacq, Xavier, Tjian, Robert
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6037474/
https://www.ncbi.nlm.nih.gov/pubmed/29939130
http://dx.doi.org/10.7554/eLife.35621