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Synergistic Anti-Cancer Effects of AKT and SRC Inhibition in Human Pancreatic Cancer Cells

PURPOSE: To investigate the effect of combined inhibition of protein kinase B (AKT) and SRC on the growth and metastatic potential of human pancreatic cancer cells. MATERIALS AND METHODS: AKT and SRC were inhibited using 10-DEBC and PP2, respectively. The expression of their messenger RNAs were down...

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Detalles Bibliográficos
Autores principales: Ahn, Kang, O, Young Moon, Ji, Young Geon, Cho, Han Jun, Lee, Dong Hyeon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Yonsei University College of Medicine 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6037593/
https://www.ncbi.nlm.nih.gov/pubmed/29978609
http://dx.doi.org/10.3349/ymj.2018.59.6.727