Optimization of a MT1-MMP-targeting Peptide and Its Application in Near-infrared Fluorescence Tumor Imaging

Membrane type 1 metalloproteinase (MT1-MMP) is an important regulator of cancer invasion, growth and angiogenesis, thus making it an attractive target for cancer imaging and therapy. A non-substrate peptide (MT1-AF7p) that bonded to the “MT-Loop” region of MT1-MMP was identified by using a phage-dis...

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Detalles Bibliográficos
Autores principales: Ren, Li, Wang, Ye, Zhu, Lei, Shen, Liqiao, Zhang, Jinrui, Wang, Jingjing, Li, Haolong, Zheng, Qingchuan, Yu, Dahai, Fang, Xuexun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6037669/
https://www.ncbi.nlm.nih.gov/pubmed/29985410
http://dx.doi.org/10.1038/s41598-018-28493-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6037669/
https://www.ncbi.nlm.nih.gov/pubmed/29985410
http://dx.doi.org/10.1038/s41598-018-28493-9

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