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Glucose and glutamine handling in the Sertoli cells of transgenic rats overexpressing regucalcin: plasticity towards lactate production

Sertoli cells (SCs) possess the unparalleled ability to provide the germ line with growth factors and nutrients. Although SCs can oxidize amino acids, e.g., glutamine, they mostly metabolize glucose, producing high amounts of lactate, the germ cells preferential substrate. Regucalcin (RGN) is a calc...

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Detalles Bibliográficos
Autores principales: Mateus, Inês, Feijó, Mariana, Espínola, Luís M., Vaz, Cátia V., Correia, Sara, Socorro, Sílvia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6037673/
https://www.ncbi.nlm.nih.gov/pubmed/29985416
http://dx.doi.org/10.1038/s41598-018-28668-4