mCSF-Induced Microglial Activation Prevents Myelin Loss and Promotes Its Repair in a Mouse Model of Multiple Sclerosis

A pathological hallmark of multiple sclerosis (MS) is myelin loss in brain white matter accompanied by compromised remyelination. Demyelinated lesions are deeply associated with oligodendrocyte apoptosis and a robust inflammatory response. Although various studies point towards a noxious role of inf...

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Detalles Bibliográficos
Autores principales: Laflamme, Nathalie, Cisbani, Giulia, Préfontaine, Paul, Srour, Younes, Bernier, Jordan, St-Pierre, Marie-Kim, Tremblay, Marie-Ève, Rivest, Serge
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6037698/
https://www.ncbi.nlm.nih.gov/pubmed/30018535
http://dx.doi.org/10.3389/fncel.2018.00178

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6037698/
https://www.ncbi.nlm.nih.gov/pubmed/30018535
http://dx.doi.org/10.3389/fncel.2018.00178

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