α-ketoglutarate dehydrogenase inhibition counteracts breast cancer-associated lung metastasis

Metastasis formation requires active energy production and is regulated at multiple levels by mitochondrial metabolism. The hyperactive metabolism of cancer cells supports their extreme adaptability and plasticity and facilitates resistance to common anticancer therapies. In spite the potential rele...

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Detalles Bibliográficos
Autores principales: Atlante, Sandra, Visintin, Alessia, Marini, Elisabetta, Savoia, Matteo, Dianzani, Chiara, Giorgis, Marta, Sürün, Duran, Maione, Federica, Schnütgen, Frank, Farsetti, Antonella, Zeiher, Andreas M., Bertinaria, Massimo, Giraudo, Enrico, Spallotta, Francesco, Cencioni, Chiara, Gaetano, Carlo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6037705/
https://www.ncbi.nlm.nih.gov/pubmed/29988033
http://dx.doi.org/10.1038/s41419-018-0802-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6037705/
https://www.ncbi.nlm.nih.gov/pubmed/29988033
http://dx.doi.org/10.1038/s41419-018-0802-8

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