Mass Cytometry Reveals Distinct Platelet Subtypes in Healthy Subjects and Novel Alterations in Surface Glycoproteins in Glanzmann Thrombasthenia

Mass cytometry (MC) uses mass spectrometry to simultaneously detect multiple metal-conjugated antibodies on single cells, thereby enabling the detailed study of cellular function. Here, for the first time, we applied MC to the analysis of platelets. We developed a panel of 14 platelet-specific metal...

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Detalles Bibliográficos
Autores principales: Blair, Thomas A., Michelson, Alan D., Frelinger, Andrew L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6037710/
https://www.ncbi.nlm.nih.gov/pubmed/29985398
http://dx.doi.org/10.1038/s41598-018-28211-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6037710/
https://www.ncbi.nlm.nih.gov/pubmed/29985398
http://dx.doi.org/10.1038/s41598-018-28211-5

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