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Dynamic behavior of DNA topoisomerase IIβ in response to DNA double-strand breaks

DNA topoisomerase II (Topo II) is crucial for resolving topological problems of DNA and plays important roles in various cellular processes, such as replication, transcription, and chromosome segregation. Although DNA topology problems may also occur during DNA repair, the possible involvement of To...

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Detalles Bibliográficos
Autores principales: Morotomi-Yano, Keiko, Saito, Shinta, Adachi, Noritaka, Yano, Ken-ichi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6037730/
https://www.ncbi.nlm.nih.gov/pubmed/29985428
http://dx.doi.org/10.1038/s41598-018-28690-6