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ER stress regulating protein phosphatase 2A-B56γ, targeted by hepatitis B virus X protein, induces cell cycle arrest and apoptosis of hepatocytes

Hepatitis B virus X (HBx) protein contributes to the progression of hepatitis B virus (HBV)-related hepatic injury and diseases, but the exact mechanism remains unclear. Protein phosphatase 2 A (PP2A) is a major serine/threonine phosphatase involved in regulating many cellular phosphorylation signal...

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Detalles Bibliográficos
Autores principales: He, Chengyong, Qiu, Yang, Han, Peiyu, Chen, Yuanyuan, Zhang, Liyin, Yuan, Quan, Zhang, Tianying, Cheng, Tong, Yuan, Lunzhi, Huang, Chenghao, Zhang, Sheng, Yin, Zhenyu, Peng, Xian-E., Liang, Dong, Lin, Xu, Lin, Yuchun, Lin, Zhongning, Xia, Ningshao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6037732/
https://www.ncbi.nlm.nih.gov/pubmed/29988038
http://dx.doi.org/10.1038/s41419-018-0787-3