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ER stress regulating protein phosphatase 2A-B56γ, targeted by hepatitis B virus X protein, induces cell cycle arrest and apoptosis of hepatocytes
Hepatitis B virus X (HBx) protein contributes to the progression of hepatitis B virus (HBV)-related hepatic injury and diseases, but the exact mechanism remains unclear. Protein phosphatase 2 A (PP2A) is a major serine/threonine phosphatase involved in regulating many cellular phosphorylation signal...
Autores principales: | He, Chengyong, Qiu, Yang, Han, Peiyu, Chen, Yuanyuan, Zhang, Liyin, Yuan, Quan, Zhang, Tianying, Cheng, Tong, Yuan, Lunzhi, Huang, Chenghao, Zhang, Sheng, Yin, Zhenyu, Peng, Xian-E., Liang, Dong, Lin, Xu, Lin, Yuchun, Lin, Zhongning, Xia, Ningshao |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6037732/ https://www.ncbi.nlm.nih.gov/pubmed/29988038 http://dx.doi.org/10.1038/s41419-018-0787-3 |
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