Assembly and activation of the Hippo signalome by FAT1 tumor suppressor

Dysregulation of the Hippo signaling pathway and the consequent YAP1 activation is a frequent event in human malignancies, yet the underlying molecular mechanisms are still poorly understood. A pancancer analysis of core Hippo kinases and their candidate regulating molecules revealed few alterations...

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Detalles Bibliográficos
Autores principales: Martin, Daniel, Degese, Maria S., Vitale-Cross, Lynn, Iglesias-Bartolome, Ramiro, Valera, Juan Luis Callejas, Wang, Zhiyong, Feng, Xiaodong, Yeerna, Huwate, Vadmal, Vachan, Moroishi, Toshiro, Thorne, Rick F., Zaida, Moraima, Siegele, Bradford, Cheong, Sok C., Molinolo, Alfredo A., Samuels, Yardena, Tamayo, Pablo, Guan, Kun Liang, Lippman, Scott M., Lyons, J. Guy, Gutkind, J. Silvio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6037762/
https://www.ncbi.nlm.nih.gov/pubmed/29985391
http://dx.doi.org/10.1038/s41467-018-04590-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6037762/
https://www.ncbi.nlm.nih.gov/pubmed/29985391
http://dx.doi.org/10.1038/s41467-018-04590-1

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