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Cross-talk between the transcription factor Sp1 and C/EBPβ modulates TGFβ1 production to negatively regulate the expression of chemokine RANTES

RANTES is a key chemokine for atherosclerosis, and obesity is associated with progression of atherosclerosis. Substance P (SP) increases glucose uptake and accumulation of lipids in adipocytes, and SP may upregulate RANTES expression. This study investigated the mechanism of RANTES expression by hum...

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Detalles Bibliográficos
Autores principales: Sakamoto, Arisa, Yamaguchi, Rui, Yamaguchi, Reona, Narahara, Shinji, Sugiuchi, Hiroyuki, Yamaguchi, Yasuo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6037877/
https://www.ncbi.nlm.nih.gov/pubmed/29998198
http://dx.doi.org/10.1016/j.heliyon.2018.e00679