Transgenic overexpression of the SUR2A-55 splice variant in mouse heart reduces infract size and promotes protective mitochondrial function

ATP-sensitive potassium channels found in both the sarcolemma (sarcK(ATP)) and mitochondria (mitoK(ATP)) of cardiomyocytes are important mediators of cardioprotection during ischemic heart disease. Sulfonylurea receptor isoforms (SUR2), encoded by Abcc9, an ATP-binding cassette family member, form r...

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Detalles Bibliográficos
Autores principales: Ramratnam, Mohun, Kenny, Barrett, Kyle, John W., Wiedmeyer, Brandi, Hacker, Timothy A., Barefield, David Y., McNally, Elizabeth M., Makielski, Jonathan C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6037880/
https://www.ncbi.nlm.nih.gov/pubmed/29998196
http://dx.doi.org/10.1016/j.heliyon.2018.e00677

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6037880/
https://www.ncbi.nlm.nih.gov/pubmed/29998196
http://dx.doi.org/10.1016/j.heliyon.2018.e00677

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