ISO, via Upregulating MiR-137 Transcription, Inhibits GSK3β-HSP70-MMP-2 Axis, Resulting in Attenuating Urothelial Cancer Invasion

Our most recent studies demonstrate that miR-137 is downregulated in human bladder cancer (BC) tissues, while treatment of human BC cells with isorhapontigenin (ISO) elevates miR-137 abundance. Since ISO showed a strong inhibition of invasive BC formation in the N-butyl-N-(4-hydroxybutyl) nitrosamin...

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Detalles Bibliográficos
Autores principales: Guo, Xirui, Huang, Haishan, Jin, Honglei, Xu, Jiheng, Risal, Sanjiv, Li, Jingxia, Li, Xin, Yan, Huiying, Zeng, Xingruo, Xue, Lei, Chen, Changyan, Huang, Chuanshu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6037888/
https://www.ncbi.nlm.nih.gov/pubmed/30195772
http://dx.doi.org/10.1016/j.omtn.2018.05.017

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6037888/
https://www.ncbi.nlm.nih.gov/pubmed/30195772
http://dx.doi.org/10.1016/j.omtn.2018.05.017

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