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Challenging the Drug-Likeness Dogma for New Drug Discovery in Tuberculosis

The emergence of multi- and extensively drug resistant tuberculosis worldwide poses a great threat to human health and highlight the need to discover and develop new, effective and inexpensive antituberculosis agents. High-throughput screening assays against well-validated drug targets and structure...

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Detalles Bibliográficos
Autores principales: Machado, Diana, Girardini, Miriam, Viveiros, Miguel, Pieroni, Marco
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6037898/
https://www.ncbi.nlm.nih.gov/pubmed/30018597
http://dx.doi.org/10.3389/fmicb.2018.01367