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Challenging the Drug-Likeness Dogma for New Drug Discovery in Tuberculosis
The emergence of multi- and extensively drug resistant tuberculosis worldwide poses a great threat to human health and highlight the need to discover and develop new, effective and inexpensive antituberculosis agents. High-throughput screening assays against well-validated drug targets and structure...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6037898/ https://www.ncbi.nlm.nih.gov/pubmed/30018597 http://dx.doi.org/10.3389/fmicb.2018.01367 |