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Efficient Multiplex Genome Editing Induces Precise, and Self-Ligated Type Mutations in Tomato Plants

Several expression systems for multiple guide RNA (gRNAs) have been developed in the CRISPR/Cas9 (clustered regularly interspaced short palindromic repeats/CRISPR associated protein 9) system to induce multiple-gene modifications in plants. Here, we evaluated mutation efficiencies in the tomato geno...

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Detalles Bibliográficos
Autores principales: Hashimoto, Ryosuke, Ueta, Risa, Abe, Chihiro, Osakabe, Yuriko, Osakabe, Keishi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6037947/
https://www.ncbi.nlm.nih.gov/pubmed/30018630
http://dx.doi.org/10.3389/fpls.2018.00916