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Selective Osmotic Shock for Islet Isolation in the Cadaveric Canine Pancreas

Currently, islet isolation is performed using harsh collagenases that cause nonspecific injury to both islets and exocrine tissue, negatively affecting the outcome of cell transplantation. We evaluated a novel islet isolation protocol utilizing high concentrations of glucose to cause selective osmot...

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Detalles Bibliográficos
Autores principales: Thompson, Elizabeth M., Sollinger, Jennifer L., Opara, Emmanuel C., Adin, Christopher A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6038033/
https://www.ncbi.nlm.nih.gov/pubmed/29869518
http://dx.doi.org/10.1177/0963689717752947