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IDO-expressing Fibroblasts Suppress the Development of Imiquimod-induced Psoriasis-like Dermatitis

Psoriasis is a chronic skin condition whose pathogenesis is reported to be due to the activation of the interleukin-23/interleukin-17 (IL-23/IL-17) pathway. Here, we report that indoleamine 2,3-dioxygenase (IDO)-expressing fibroblasts reduce the activity of this pathway in activated immune cells. Th...

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Detalles Bibliográficos
Autores principales: Elizei, Sanam Salimi, Pakyari, Mohammadreza, Ghoreishi, Mehraneh, Kilani, Ruhangiz, Mahmoudi, Sanaz, Ghahary, Aziz
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6038037/
https://www.ncbi.nlm.nih.gov/pubmed/29759005
http://dx.doi.org/10.1177/0963689718757482