ACE gene dosage determines additional autonomic dysfunction and increases renal angiotensin II levels in diabetic mice

OBJECTIVES: The present study aimed to investigate cardiovascular autonomic modulation and angiotensin II (Ang II) activity in diabetic mice that were genetically engineered to harbor two or three copies of the angiotensin-converting enzyme gene. METHODS: Diabetic and non-diabetic mice harboring 2 o...

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Detalles Bibliográficos
Autores principales: de Moraes, Oscar Albuquerque, Flues, Karin, Scapini, Kátia Bilhar, Mostarda, Cristiano, Evangelista, Fabiana de Sant’Anna, Rodrigues, Bruno, Dartora, Daniela Ravizzoni, Fiorino, Patricia, Angelis, Kátia De, Irigoyen, Maria Cláudia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo 2018
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6038058/
https://www.ncbi.nlm.nih.gov/pubmed/30088535
http://dx.doi.org/10.6061/clinics/2018/e246

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6038058/
https://www.ncbi.nlm.nih.gov/pubmed/30088535
http://dx.doi.org/10.6061/clinics/2018/e246

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