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A role for telomere length and chromosomal damage in idiopathic pulmonary fibrosis

BACKGROUND: Idiopathic pulmonary fibrosis is a fatal lung disease characterized by a progressive formation of fibroblastic foci in the interstitium. This disease is strongly associated with telomere dysfunction but the extent of telomere shortening and consequent chromosomal damage within IPF lungs...

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Detalles Bibliográficos
Autores principales: McDonough, John E., Martens, Dries S., Tanabe, Naoya, Ahangari, Farida, Verleden, Stijn E., Maes, Karen, Verleden, Geert M., Kaminski, Naftali, Hogg, James C., Nawrot, Tim S., Wuyts, Wim A., Vanaudenaerde, Bart M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6038197/
https://www.ncbi.nlm.nih.gov/pubmed/29986708
http://dx.doi.org/10.1186/s12931-018-0838-4