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miR-182 suppresses invadopodia formation and metastasis in non-small cell lung cancer by targeting cortactin gene
BACKGROUND: Metastasis is the leading cause of cancer mortality and is a major hurdle for lung cancer treatment. Invadopodia, which are cancer-specific protrusive structures, play a crucial role in the metastatic cascade through degradation of the basement membrane and surrounding stroma. Cortactin,...
Autores principales: | , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6038252/ https://www.ncbi.nlm.nih.gov/pubmed/29986736 http://dx.doi.org/10.1186/s13046-018-0824-1 |