Stepwise approach to SNP-set analysis illustrated with the Metabochip and colorectal cancer in Japanese Americans of the Multiethnic Cohort

BACKGROUND: Common variants have explained less than the amount of heritability expected for complex diseases, which has led to interest in less-common variants and more powerful approaches to the analysis of whole-genome scans. Because of low frequency (low statistical power), less-common variants...

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Detalles Bibliográficos
Autores principales: Cologne, John, Loo, Lenora, Shvetsov, Yurii B., Misumi, Munechika, Lin, Philip, Haiman, Christopher A., Wilkens, Lynne R., Le Marchand, Loïc
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Methodology Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6038257/
https://www.ncbi.nlm.nih.gov/pubmed/29986644
http://dx.doi.org/10.1186/s12864-018-4910-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6038257/
https://www.ncbi.nlm.nih.gov/pubmed/29986644
http://dx.doi.org/10.1186/s12864-018-4910-8

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