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Memory T cells skew toward terminal differentiation in the CD8+ T cell population in patients with acute myeloid leukemia

Stem cell memory T (T(SCM)) and central memory T (T(CM)) cells can rapidly differentiate into effector memory (T(EM)) and terminal effector (T(EF)) T cells, and have the most potential for immunotherapy. In this study, we found that the frequency of T(SCM) and T(CM) cells in the CD8+ population dram...

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Detalles Bibliográficos
Autores principales: Xu, Ling, Yao, Danlin, Tan, Jiaxiong, He, Zifan, Yu, Zhi, Chen, Jie, Luo, Gengxin, Wang, Chunli, Zhou, Fenfang, Zha, Xianfeng, Chen, Shaohua, Li, Yangqiu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6038290/
https://www.ncbi.nlm.nih.gov/pubmed/29986734
http://dx.doi.org/10.1186/s13045-018-0636-y