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NOX4 expression and distal arteriolar remodeling correlate with pulmonary hypertension in COPD

BACKGROUND: Pulmonary hypertension (PH) in chronic obstructive pulmonary disease (COPD) is suggested as the consequence of emphysematous destruction of vascular bed and hypoxia of pulmonary microenvironment, mechanisms underpinning its pathogenesis however remain elusive. The dysregulated expression...

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Detalles Bibliográficos
Autores principales: Guo, Xiaotong, Fan, Yuchun, Cui, Jieda, Hao, Binwei, Zhu, Li, Sun, Xiao, He, Jinxi, Yang, Jiali, Dong, Jianda, Wang, Yanyang, Liu, Xiaoming, Chen, Juan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6038356/
https://www.ncbi.nlm.nih.gov/pubmed/29986678
http://dx.doi.org/10.1186/s12890-018-0680-y