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Pro-BDNF Contributes to Hypoxia/Reoxygenation Injury in Myocardial Microvascular Endothelial Cells: Roles of Receptors p75(NTR) and Sortilin and Activation of JNK and Caspase 3

The aim of this study was to identify the role of the precursor of the brain-derived neurotrophic factor (pro-BDNF) in myocardial hypoxia/reoxygenation injury (H/R) and to address the underlying mechanisms. For this purpose, myocardial microvascular endothelial cells (MMECs) exposed to a high concen...

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Detalles Bibliográficos
Autores principales: Yu, Fei, Liu, Yuezhu, Xu, Junmei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6038493/
https://www.ncbi.nlm.nih.gov/pubmed/30046375
http://dx.doi.org/10.1155/2018/3091424