Diagnosis of Methionine/Valine Variant Creutzfeldt-Jakob Disease by Protein Misfolding Cyclic Amplification

A patient with a heterozygous variant of Creutzfeldt-Jakob disease (CJD) with a methionine/valine genotype at codon 129 of the prion protein gene was recently reported. Using an ultrasensitive and specific protein misfolding cyclic amplification–based assay for detecting variant CJD prions in cerebr...

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Detalles Bibliográficos
Autores principales: Bougard, Daisy, Bélondrade, Maxime, Mayran, Charly, Bruyère-Ostells, Lilian, Lehmann, Sylvain, Fournier-Wirth, Chantal, Knight, Richard S., Will, Robert G., Green, Alison J.E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Centers for Disease Control and Prevention 2018
Materias:
Dispatch
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6038758/
https://www.ncbi.nlm.nih.gov/pubmed/29912702
http://dx.doi.org/10.3201/eid2407.172105

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6038758/
https://www.ncbi.nlm.nih.gov/pubmed/29912702
http://dx.doi.org/10.3201/eid2407.172105

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