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Self-nanomicellizing solid dispersion of edaravone: part I – oral bioavailability improvement

BACKGROUND: Edaravone (EDR) is known for its free radical scavenging, antiapoptotic, antinecrotic, and anticytokine effects in neurological and non-neurological diseases. It is currently available clinically as Radicava(®) and Radicut(®), intravenous medications, recently approved for the treatment...

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Detalles Bibliográficos
Autores principales: Parikh, Ankit, Kathawala, Krishna, Tan, Chun Chuan, Garg, Sanjay, Zhou, Xin-Fu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6038876/
https://www.ncbi.nlm.nih.gov/pubmed/30013324
http://dx.doi.org/10.2147/DDDT.S161940