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Identification of a tyrosine switch in copper-haem nitrite reductases

There are few cases where tyrosine has been shown to be involved in catalysis or the control of catalysis despite its ability to carry out chemistry at much higher potentials (1 V versus NHE). Here, it is shown that a tyrosine that blocks the hydrophobic substrate-entry channel in copper-haem nitrit...

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Detalles Bibliográficos
Autores principales: Dong, Jianshu, Sasaki, Daisuke, Eady, Robert R., Antonyuk, Svetlana V., Hasnain, S. Samar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Union of Crystallography 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6038957/
https://www.ncbi.nlm.nih.gov/pubmed/30002851
http://dx.doi.org/10.1107/S2052252518008242