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Radiosynthesis of (11)C-phenytoin Using a DEGDEE Solvent for Clinical PET Studies

OBJECTIVE(S): Phenytoin is an antiepileptic drug that is used worldwide. The whole-body pharmacokinetics of this drug have been extensively studied using (11)C-phenytoin in small animals. However, because of the limited production amounts that are presently available, clinical (11)C-phenytoin PET st...

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Detalles Bibliográficos
Autores principales: Kanai, Yasukazu, Miyake, Yoshinori, Shimosegawa, Eku, Hatazawa, Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Mashhad University of Medical Sciences 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6038967/
https://www.ncbi.nlm.nih.gov/pubmed/29998148
http://dx.doi.org/10.22038/aojnmb.2018.10846