An amyloidogenic hexapeptide derived from amylin attenuates inflammation and acute lung injury in murine sepsis

Although the accumulation of amyloidogenic proteins in neuroinflammatory conditions is generally considered pathologic, in a murine model of multiple sclerosis, amyloid-forming fibrils, comprised of hexapeptides, are anti-inflammatory. Whether these molecules modulate systemic inflammatory condition...

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Detalles Bibliográficos
Autores principales: Mahapatra, Sidharth, Ying, Lihua, Ho, Peggy Pui-Kay, Kurnellas, Michael, Rothbard, Jonathan, Steinman, Lawrence, Cornfield, David N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6039005/
https://www.ncbi.nlm.nih.gov/pubmed/29990318
http://dx.doi.org/10.1371/journal.pone.0199206

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6039005/
https://www.ncbi.nlm.nih.gov/pubmed/29990318
http://dx.doi.org/10.1371/journal.pone.0199206

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