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An amyloidogenic hexapeptide derived from amylin attenuates inflammation and acute lung injury in murine sepsis
Although the accumulation of amyloidogenic proteins in neuroinflammatory conditions is generally considered pathologic, in a murine model of multiple sclerosis, amyloid-forming fibrils, comprised of hexapeptides, are anti-inflammatory. Whether these molecules modulate systemic inflammatory condition...
Autores principales: | Mahapatra, Sidharth, Ying, Lihua, Ho, Peggy Pui-Kay, Kurnellas, Michael, Rothbard, Jonathan, Steinman, Lawrence, Cornfield, David N. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6039005/ https://www.ncbi.nlm.nih.gov/pubmed/29990318 http://dx.doi.org/10.1371/journal.pone.0199206 |
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