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Intracellular attenuation of BMP signaling via CKIP-1/Smurf1 is essential during neural crest induction

The neural crest is induced at the neural plate border during gastrulation by combined bone morphogenetic protein (BMP), fibroblast growth factor (FGF), and Wnt signaling. While intermediate BMP levels are critical for this induction, secreted BMP inhibitors are largely absent from the neural plate...

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Detalles Bibliográficos
Autores principales: Piacentino, Michael L., Bronner, Marianne E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6039030/
https://www.ncbi.nlm.nih.gov/pubmed/29949573
http://dx.doi.org/10.1371/journal.pbio.2004425