Flavonoid compound icariin enhances BMP-2 induced differentiation and signalling by targeting to connective tissue growth factor (CTGF) in SAMP6 osteoblasts

BACKGROUND: Icariin, a major active flavonoid glucoside, is widely used for the treatment of bone injury and rebuilding in the clinic because of its roles in suppressing osteoblastogenesis and promoting osteogenesis. The senescence-accelerated mouse SAMP6 was accepted as a useful murine model to rev...

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Detalles Bibliográficos
Autores principales: Xu, Bing, Wang, Xueqiang, Wu, Chengliang, Zhu, Lihe, Chen, Ou, Wang, Xiaofeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6039035/
https://www.ncbi.nlm.nih.gov/pubmed/29990327
http://dx.doi.org/10.1371/journal.pone.0200367

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6039035/
https://www.ncbi.nlm.nih.gov/pubmed/29990327
http://dx.doi.org/10.1371/journal.pone.0200367

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